RNA-directed DNA synthesis and RNA tumor viruses.

@article{Temin1972RNAdirectedDS,
  title={RNA-directed DNA synthesis and RNA tumor viruses.},
  author={Howard M. Temin and David Baltimore},
  journal={Advances in virus research},
  year={1972},
  volume={17},
  pages={
          129-86
        }
}
Publisher Summary The discovery of RNA-directed DNA synthesis in disrupted virions of RNA tumor viruses added strong support to the hypothesis that information transfer from RNA to DNA exists in biological system. The chapter discusses the properties of the endogenous reaction carried out by the virion DNA polymerase. To study the endogenous reaction disrupted, virions are incubated with substrates in the absence of any added template and synthesis of DNA is observed using the RNA present in… CONTINUE READING
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