RNA-directed DNA methylation and Pol IVb in Arabidopsis.

@article{Matzke2006RNAdirectedDM,
  title={RNA-directed DNA methylation and Pol IVb in Arabidopsis.},
  author={Marjori Matzke and Tatsuo Kanno and Bruno H{\"u}ttel and Lucia Clemens- Daxinger and Antonius J. M. Matzke},
  journal={Cold Spring Harbor symposia on quantitative biology},
  year={2006},
  volume={71},
  pages={449-59}
}
Recent work in Arabidopsis has revealed a plant-specific RNA polymerase, pol IV, that is specialized for RNA interference (RNAi)-mediated, chromatin-based gene silencing. Two functionally diversified pol IV complexes have been identified: pol IVa is required to produce or amplify the small RNA trigger, whereas pol IVb, together with the plant-specific SWI/SNF-like chromatin remodeling factor DRD1, acts downstream from small RNA formation to induce de novo cytosine methylation of homologous DNA… CONTINUE READING

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