RNA-catalysed nucleotide synthesis

@article{Unrau1998RNAcatalysedNS,
  title={RNA-catalysed nucleotide synthesis},
  author={Peter J. Unrau and David P. Bartel},
  journal={Nature},
  year={1998},
  volume={395},
  pages={260-263}
}
The ‘RNA world’ hypothesis proposes that early life developed by making use of RNA molecules, rather than proteins, to catalyse the synthesis of important biological molecules. It is thought, however, that the nucleotides constituting RNA were scarce on early Earth. RNA-based life must therefore have acquired the ability to synthesize RNA nucleotides from simpler and more readily available precursors, such as sugars and bases. Plausible prebiotic synthesis routes have been proposed for sugars… Expand
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