RNA-binding proteins come out of the shadows

  title={RNA-binding proteins come out of the shadows},
  author={Jelena Nedjic and Iannis Aifantis},
  journal={Nature Immunology},
nature immunology volume 11 number 8 AuGuST 2010 697 CD4+CD8+ double-positive cells, the typical feature of mouse models of T-ALL3. To gain a deeper insight into the molecular mechanisms perturbed in ZFP36L1and ZFP36L2-dKO thymocytes, the authors use transcriptome analyses to identify their putative targets. After stringent data evaluation, they identify only 17 genes whose mRNA is significantly stabilized after genetic ablation of ZFP36L1 and ZFP36L 2. Of all the candidates identified, Notch1… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.


Publications referenced by this paper.

Oncogene published online, doi:10.1038/onc.2010.168

  • C. Mayr, D. P. Bartel
  • Cell 138,
  • 2009

Similar Papers

Loading similar papers…