RNA backbone is rotameric.

  title={RNA backbone is rotameric.},
  author={Laura Weston Murray and W. Bryan Arendall and David C. Richardson and Jane S. Richardson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={100 24},
Despite the importance of local structural detail to a mechanistic understanding of RNA catalysis and binding functions, RNA backbone conformation has been quite recalcitrant to analysis. There are too many variable torsion angles per residue, and their raw empirical distributions are poorly clustered. This study applies quality-filtering techniques (using resolution, crystallographic B factor, and all-atom steric clashes) to the backbone torsion angle distributions from an 8,636-residue RNA… CONTINUE READING
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