RNA as a tumor vaccine: a review of the literature.

  title={RNA as a tumor vaccine: a review of the literature.},
  author={J Saenz-Badillos and Snehal P Amin and Richard D Granstein},
  journal={Experimental dermatology},
  volume={10 3},
Many approaches have been attempted to harness the host immune system to act against malignant tumors. These have included animal and clinical trials with agents to non-specifically boost immunity, factors to augment specific immunity, transfer of lymphokine-activated killer cells and transfer of expanded populations of tumor-infiltrating lymphocytes. Therapeutic vaccination strategies have been employed using tumor extracts, purified tumor antigens, recombinant peptide tumor antigens and… CONTINUE READING


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