RNA and protein 3D structure modeling: similarities and differences

@inproceedings{Rother2011RNAAP,
  title={RNA and protein 3D structure modeling: similarities and differences},
  author={Kristian M. Rother and Magdalena Rother and Michał J Boniecki and Tomasz Puton and Janusz M. Bujnicki},
  booktitle={Journal of molecular modeling},
  year={2011}
}
In analogy to proteins, the function of RNA depends on its structure and dynamics, which are encoded in the linear sequence. While there are numerous methods for computational prediction of protein 3D structure from sequence, there have been very few such methods for RNA. This review discusses template-based and template-free approaches for macromolecular structure prediction, with special emphasis on comparison between the already tried-and-tested methods for protein structure modeling and the… CONTINUE READING
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