RNA and DNA nanoparticles for triggering RNA interference
@article{Tannir2015RNAAD, title={RNA and DNA nanoparticles for triggering RNA interference}, author={Ziad El Tannir and Kirill A Afonin and B. Shapiro}, journal={RNA & DISEASE}, year={2015}, volume={2} }
Control over the delivery of different functionalities and their synchronized activation in vivo is a challenging undertaking that requires careful design and implementation. The goal of the research highlighted herein was to develop a platform allowing the simultaneous activation of multiple RNA interference pathways and other functionalities inside cells. Our team has developed several RNA, RNA/DNA and DNA/RNA nanoparticles able to successfully complete such tasks. The reported designs can… CONTINUE READING
Figures from this paper
Figures
References
SHOWING 1-10 OF 33 REFERENCES
Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles
- Biology, Medicine
- ACS nano
- 2015
- 72
Co-transcriptional assembly of chemically modified RNA nanoparticles functionalized with siRNAs.
- Medicine, Materials Science
- Nano letters
- 2012
- 89
In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles
- Medicine, Chemistry
- Accounts of chemical research
- 2014
- 57
Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine
- Biology, Medicine
- Nature Protocols
- 2011
- 133
Co-transcriptional production of RNA–DNA hybrids for simultaneous release of multiple split functionalities
- Biology, Medicine
- Nucleic acids research
- 2014
- 41
Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology.
- Chemistry, Medicine
- Nano letters
- 2005
- 210
- PDF
Activation of different split functionalities upon re-association of RNA-DNA hybrids
- Chemistry, Medicine
- Nature nanotechnology
- 2013
- 80