RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion

@inproceedings{Vijaykrishna2015RNAVR,
  title={RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion},
  author={Dhanasekaran Vijaykrishna and Reshmi Mukerji and Gavin J D Smith and Rebecca Ellis Dutch},
  booktitle={PLoS pathogens},
  year={2015}
}
Reassortment is an evolutionary mechanism of segmented RNA viruses that plays an important but ill-defined role in virus emergence and interspecies transmission. Recent experimental studies have greatly enhanced our understanding of the cellular mechanisms of reassortment within a host cell. Our purpose here is to offer a brief introduction on the role of reassortment in segmented RNA virus evolution, explain the host cellular mechanisms of reassortment, and provide a synthesis of recent… CONTINUE READING
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