RNA Turnover: Unexpected Consequences of Being Tailed

@article{Anderson2005RNATU,
  title={RNA Turnover: Unexpected Consequences of Being Tailed},
  author={JamesC . Anderson},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={R635-R638}
}
In eukaryotic cells, the 3' poly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3' end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function. 
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References

SHOWING 1-10 OF 37 REFERENCES
Yeast Exosome Mutants Accumulate 3′-Extended Polyadenylated Forms of U4 Small Nuclear RNA and Small Nucleolar RNAs
mRNA decay in Escherichia coli comes of age.
...
1
2
3
4
...