RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures

@article{Pellegrino2016RNASeqFP,
  title={RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures},
  author={Maurizio Pellegrino and Adam Sciambi and Jamie Yates and Joshua D Mast and Charles Silver and Dennis J. Eastburn},
  journal={BMC Genomics},
  year={2016},
  volume={17},
  pages={1-12}
}
BackgroundRare cell subtypes can profoundly impact the course of human health and disease, yet their presence within a sample is often missed with bulk molecular analysis. Single-cell analysis tools such as FACS, FISH-FC and single-cell barcode-based sequencing can investigate cellular heterogeneity; however, they have significant limitations that impede their ability to identify and transcriptionally characterize many rare cell subpopulations.ResultsPCR-activated cell sorting (PACS) is a novel… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 57 REFERENCES

Various R Programming Tools for Plotting Data

G Warnes, B Bolker, +8 authors gplots et al.
  • 2015. • We accept pre-submission inquiries • Our selector tool helps you to find the most relevant journal • We provide round the clock customer support • Convenient online submission • Thorough peer review • Inclusion in PubMed and all major indexing services • Maximum visibility for your research
  • 2016
VIEW 1 EXCERPT