RNA-Seq and RNA immunoprecipitation analyses of the transcriptome of Streptomyces coelicolor identify substrates for RNase III.

@article{Gatewood2012RNASeqAR,
  title={RNA-Seq and RNA immunoprecipitation analyses of the transcriptome of Streptomyces coelicolor identify substrates for RNase III.},
  author={Marcha L. Gatewood and Patricia Bralley and Michael Ryan Weil and George H. Jones},
  journal={Journal of bacteriology},
  year={2012},
  volume={194 9},
  pages={2228-37}
}
RNase III is a key enzyme in the pathways of RNA degradation and processing in bacteria and has been suggested as a global regulator of antibiotic production in Streptomyces coelicolor. Using RNA-Seq, we have examined the transcriptomes of S. coelicolor M145 and an RNase III (rnc)-null mutant of that strain. RNA preparations with reduced levels of… CONTINUE READING