RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

  title={RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia},
  author={Junzhe Xu and Jingchun Sun and Jingchun Chen and Lily Wang and Anna S Li and Matthew F. Helm and Steven L. Dubovsky and Silviu Bacanu and Zhongming Zhao and Xiangning Chen},
  booktitle={BMC Genomics},
While genome-wide association studies identified some promising candidates for schizophrenia, the majority of risk genes remained unknown. We were interested in testing whether integration gene expression and other functional information could facilitate the identification of susceptibility genes and related biological pathways. We conducted high throughput sequencing analyses to evaluate mRNA expression in blood samples isolated from 3 schizophrenia patients and 3 healthy controls. We also… CONTINUE READING
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