RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

@inproceedings{Xu2012RNASeqAI,
  title={RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia},
  author={Junzhe Xu and Jingchun Sun and Jingchun Chen and Lily Wang and Anna S Li and Matthew F. Helm and Steven L. Dubovsky and Silviu Bacanu and Zhongming Zhao and Xiangning Chen},
  booktitle={BMC Genomics},
  year={2012}
}
While genome-wide association studies identified some promising candidates for schizophrenia, the majority of risk genes remained unknown. We were interested in testing whether integration gene expression and other functional information could facilitate the identification of susceptibility genes and related biological pathways. We conducted high throughput sequencing analyses to evaluate mRNA expression in blood samples isolated from 3 schizophrenia patients and 3 healthy controls. We also… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Glioma in Schizophrenia: Is the Risk Higher or Lower?

Front. Cell. Neurosci. • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 64 references

HLA-B maternal-fetal genotype matching increases risk of schizophrenia.

American journal of human genetics • 2006
View 7 Excerpts
Highly Influenced

Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 4 Excerpts
Highly Influenced

HTseq Program. 2012 [http://www-huber.embl.de/users/ anders/HTSeq/

Simon Anders
2012
View 2 Excerpts

Immunohistochemical characterization of microglia in Nasu-Hakola disease brains.

Neuropathology : official journal of the Japanese Society of Neuropathology • 2011
View 1 Excerpt

Similar Papers

Loading similar papers…