RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans

@inproceedings{AmorimVaz2015RNAEM,
  title={RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans},
  author={Sara Amorim-Vaz and Van Du T Tran and Sylvain Pradervand and Marco Pagni and Alix Therese Coste and Dominique Sanglard},
  booktitle={mBio},
  year={2015}
}
UNLABELLED In vivo transcriptional analyses of microbial pathogens are often hampered by low proportions of pathogen biomass in host organs, hindering the coverage of full pathogen transcriptome. We aimed to address the transcriptome profiles of Candida albicans, the most prevalent fungal pathogen in systemically infected immunocompromised patients, during systemic infection in different hosts. We developed a strategy for high-resolution quantitative analysis of the C. albicans transcriptome… CONTINUE READING
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