RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing

@article{Ahlquist2002RNADependentRP,
  title={RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing},
  author={P. Ahlquist},
  journal={Science},
  year={2002},
  volume={296},
  pages={1270 - 1273}
}
Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA–dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing. Although the viral and cellular RdRps have no sequence homology, they share functional similarities such as copying messenger RNA templates and intercellular spread of the… Expand
413 Citations
The dependence of viral RNA replication on co-opted host factors
  • 318
  • PDF
Common and unique features of viral RNA-dependent polymerases
  • 76
  • PDF
The role of virus-derived small interfering RNAs in RNA silencing in plants
  • H. Zhu, H. Guo
  • Biology, Medicine
  • Science China Life Sciences
  • 2012
  • 25
  • PDF
Common and unique features of viral RNA-dependent polymerases
  • 65
  • PDF
Host Factors Promoting Viral RNA Replication
  • 2
Strategies underlying RNA silencing suppression by negative strand RNA viruses
  • 1
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 66 REFERENCES
Switch from translation to RNA replication in a positive-stranded RNA virus.
  • 502
  • PDF
Induction and Suppression of RNA Silencing by an Animal Virus
  • 823
  • PDF
RNA recombination in animal and plant viruses.
  • M. Lai
  • Biology, Medicine
  • Microbiological reviews
  • 1992
  • 267
  • PDF
...
1
2
3
4
5
...