RNA Binding Protein/RNA Element Interactions and the Control of Translation

  title={RNA Binding Protein/RNA Element Interactions and the Control of Translation},
  author={Xavier Le Pichon and Lindsay A. Wilson and Mark Stoneley and Amandine Bastide and Helen A King and Joanna Somers and Anne E. Willis},
  booktitle={Current protein & peptide science},
A growing body of work demonstrates the importance of post-transcriptional control, in particular translation initiation, in the overall regulation of gene expression. Here we focus on the contribution of regulatory elements within the 5' and 3' untranslated regions of mRNA to gene expression in eukaryotic cells including terminal oligopyrimidine tracts, internal ribosome entry segments, upstream open reading frames and cytoplasmic polyadenylation elements. These mRNA regulatory elements may… CONTINUE READING
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