RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription.

@article{Sonmez2011RNA3P,
  title={RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription.},
  author={Cagla Sonmez and Isabel B{\"a}urle and Andreas Magusin and Ren{\'e} Dreos and Sascha Laubinger and Detlef Weigel and Caroline Dean},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 20},
  pages={
          8508-13
        }
}
The RNA-binding proteins FCA and FPA were identified based on their repression of the flowering time regulator FLC but have since been shown to have widespread roles in the Arabidopsis thaliana genome. Here, we use whole-genome tiling arrays to show that a wide spectrum of genes and transposable elements are misexpressed in the fca-9 fpa-7 (fcafpa) double mutant at two stages of seedling development. There was a significant bias for misregulated genomic segments mapping to the 3' region of… CONTINUE READING

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