RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans.

@article{Zhang2001RME8AC,
  title={RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans.},
  author={Y H Zhang and B. K. Grant and David Hirsh},
  journal={Molecular biology of the cell},
  year={2001},
  volume={12 7},
  pages={
          2011-21
        }
}
By genetic analysis of Caenorhabditis elegans mutants defective in yolk uptake, we have identified new molecules functioning in the endocytosis pathway. Here we describe a novel J-domain-containing protein, RME-8, identified by such genetic analysis. RME-8 is required for receptor-mediated endocytosis and fluid-phase endocytosis in various cell types and is essential for C. elegans development and viability. In the macrophage-like coelomocytes, RME-8 localizes to the limiting membrane of large… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 72 extracted citations

Similar Papers

Loading similar papers…