RKIP and BRAF aberrations in human nasal polyps and the adjacent turbinate mucosae.

@article{Zaravinos2008RKIPAB,
  title={RKIP and BRAF aberrations in human nasal polyps and the adjacent turbinate mucosae.},
  author={Apostolos Zaravinos and John G. Bizakis and Demetrios A. Spandidos},
  journal={Cancer letters},
  year={2008},
  volume={264 2},
  pages={288-98}
}
BACKGROUND Little is known about the implication of BRAF and RKIP expression, or about the incidence of BRAF mutations in the formation of nasal polyposis. OBJECTIVES To determine the expression levels of the genes BRAF and RKIP, and to inspect the frequency of BRAF mutations in exons 11, 14 and 15 in human nasal polyps (NP). PATIENTS AND METHODS We analyzed 24 human NP specimens and their adjacent inferior and middle turbinates (AIT and AMT), as well as 14 control subjects [bearing 14… CONTINUE READING