RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis

@inproceedings{HemanAckah2013RISCIP,
  title={RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis},
  author={Sabrina Mahalia Heman-Ackah and Martina Hallegger and Mahendra S. Rao and Matthew J. Wood},
  booktitle={Front. Mol. Neurosci.},
  year={2013}
}
Parkinson's disease (PD) is a debilitating neurodegenerative disease characterized primarily by the selective death of dopaminergic (DA) neurons in the substantia nigra pars compacta of the midbrain. Although several genetic forms of PD have been identified, the precise molecular mechanisms underlying DA neuron loss in PD remain elusive. In recent years, microRNAs (miRNAs) have been recognized as potent post-transcriptional regulators of gene expression with fundamental roles in numerous… CONTINUE READING
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