RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25

Abstract

We previously identified the important role of RIN1 expression in the prognosis of clear cell renal cell carcinoma (ccRCC). The role of RIN1 in ccRCC malignancy and underlying molecular mechanisms remain unclear. Here we report that ccRCC cells and tissues expressed more RIN1 than normal controls. Gain-of-function and loss-of-function studies demonstrated… (More)
DOI: 10.1111/cas.13297

Topics

Cite this paper

@inproceedings{Feng2017RP, title={ RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25}, author={Zi-Hao Feng and Yong Fang and Liang-yun Zhao and Jun Lu and Yong-qian Wang and Zhen-hua Chen and Yong Huang and Jin-Huan Wei and Yan-ping Liang and Jun-Jie Cen and Yi-Hui Pan and Bing Liao and Wei Chen and Jun-Hang Luo}, booktitle={Cancer science}, year={2017} }