RILA blood biomarker as a predictor of radiation-induced sarcoma in a matched cohort study☆

@inproceedings{Mirjolet2019RILABB,
  title={RILA blood biomarker as a predictor of radiation-induced sarcoma in a matched cohort study☆},
  author={C{\'e}line Mirjolet and J. L. Merlin and Gilles Truc and Guilhem Noel and Juliette Thariat and Julien D{\^o}mont and Paul Sargos and Sophie Renard-Oldrini and Isabelle Ray-Coquard and Xavier Liem and Christine Chevreau and J. L. Lagrange and M A Mah{\'e} and François Collin and Franck. Bonnetain and Aur{\'e}lie Bertaut and Philippe Maingon},
  booktitle={EBioMedicine},
  year={2019}
}
PURPOSE Radiation-induced sarcoma (RIS) is a rare but serious event. Its occurrence has been discussed during the implementation of new radiation techniques and justified appropriate radioprotection requirements. New approaches targeting intrinsic radio-sensitivity have been described, such as radiation-induced CD8 T-lymphocyte apoptosis (RILA) able to predict late radio-induced toxicities. We studied the role of RILA as a predisposing factor for RIS as a late adverse event following radiation… CONTINUE READING
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