RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.

@article{LuisRavelo2014RHOBIL,
  title={RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.},
  author={Diego Luis-Ravelo and Iker Ant{\'o}n and Carolina Zandueta and Karmele Valencia and M. J. Pajares and Jackeline Agorreta and Luis M. Montuenga and Silvestre Vicent and Ignacio Wistuba and Javier De Las Rivas and Fernando Lecanda},
  journal={Molecular oncology},
  year={2014},
  volume={8 2},
  pages={196-206}
}
Lung adenocarcinoma (ADC) is the most common lung cancer subtype and presents a high mortality rate. Clinical recurrence is often associated with the emergence of metastasis and treatment resistance. The purpose of this study was to identify genes with high prometastatic activity which could potentially account for treatment resistance. Global transcriptomic profiling was performed by robust microarray analysis in highly metastatic subpopulations. Extensive in vitro and in vivo functional… CONTINUE READING
Highly Cited
This paper has 35 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…