RH locus contraction in a novel Dc-/D-- genotype resulting from separate genetic recombination events.

Abstract

BACKGROUND The rare phenotypes Dc- and D-- lack the expression of E/e and CcEe antigens, respectively; their cotransmission in a single family has not been reported. STUDY DESIGN AND METHODS Six members of a Chinese family with two exhibiting the Dc- phenotype were studied using standard serologic methods. Rh genotypes were analyzed by Southern blot, and… (More)

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