RFamide-related peptide gene is a melatonin-driven photoperiodic gene.

@article{Revel2008RFamiderelatedPG,
  title={RFamide-related peptide gene is a melatonin-driven photoperiodic gene.},
  author={Florent G. Revel and Michel Saboureau and Paul Pevet and Val{\'e}rie Simonneaux and Jens Damsgaard Mikkelsen},
  journal={Endocrinology},
  year={2008},
  volume={149 3},
  pages={
          902-12
        }
}
In seasonal species, various physiological processes including reproduction are organized by photoperiod via melatonin, but the mechanisms of melatonin action are still unknown. In birds, the peptide gonadotropin-inhibiting hormone (GnIH) has been shown to have inhibitory effects on reproductive activity and displays seasonal changes of expression. Here we present evidence in mammals that the gene orthologous to GnIH, the RFamide-related peptide (RFRP) gene, expressed in the mediobasal… CONTINUE READING
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