RFX3 Modulation of FOXJ1 regulation of cilia genes in the human airway epithelium

@inproceedings{Didon2013RFX3MO,
  title={RFX3 Modulation of FOXJ1 regulation of cilia genes in the human airway epithelium},
  author={Lukas Didon and Rachel K. Zwick and Ion Wa Chao and M. Scott Walters and Rui Wang and Neil R. Hackett and Ronald G. Crystal},
  booktitle={Respiratory research},
  year={2013}
}
BACKGROUND Ciliated cells play a central role in cleansing the airways of inhaled contaminants. They are derived from basal cells that include the airway stem/progenitor cells. In animal models, the transcription factor FOXJ1 has been shown to induce differentiation to the ciliated cell lineage, and the RFX transcription factor-family has been shown to be necessary for, but not sufficient to induce, correct cilia development. METHODS To test the hypothesis that FOXJ1 and RFX3 cooperatively… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 63 references

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 6 Excerpts
Highly Influenced

Role of f-box factor foxj1 in differentiation of ciliated airway epithelial cells.

American journal of physiology. Lung cellular and molecular physiology • 2004
View 6 Excerpts
Highly Influenced

Structure and Function of Cilia

R Lee, J Forrest
Edited by Crystal R, West J. Philadelphia: Raven Publishers; • 1997
View 5 Excerpts
Highly Influenced

Ciliated Cells of the Lungs

J Sturgess
In Lung Cell Biology. Edited by Massaro D. New York: Marcel Dekker, • 1989
View 4 Excerpts
Highly Influenced

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