RFX2 is a candidate downstream amplifier of A-MYB regulation in mouse spermatogenesis

@inproceedings{Horvath2009RFX2IA,
  title={RFX2 is a candidate downstream amplifier of A-MYB regulation in mouse spermatogenesis},
  author={Gary C Horvath and Michael K. Kistler and W. Stephen Kistler},
  booktitle={BMC Developmental Biology},
  year={2009}
}
Mammalian spermatogenesis involves formation of haploid cells from the male germline and then a complex morphological transformation to generate motile sperm. Focusing on meiotic prophase, some tissue-specific transcription factors are known (A-MYB) or suspected (RFX2) to play important roles in modulating gene expression in pachytene spermatocytes. The current work was initiated to identify both downstream and upstream regulatory connections for Rfx2. Searches of pachytene up-regulated genes… CONTINUE READING
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