Corpus ID: 37475975

REVIEWARTICLE PANDAS : a new disease ?

@inproceedings{Oliveira2007REVIEWARTICLEP,
  title={REVIEWARTICLE PANDAS : a new disease ?},
  author={Sheila Knupp Oliveira},
  year={2007}
}
Objective: To establish the diagnostic criteria for PANDAS and to analyze the existing evidence regarding its etiopathogenesis, treatment and prophylaxis. Sources: Review of the scientific literature through a MEDLINE search carried out between 1989 and 2006. Summary of the findings: The diagnostic criteria for PANDASwere established nearly 10 years ago, but a lot of controversy still exists over the actual existence of this new pediatric disease. The name of this new disease, supposedly of… Expand

References

SHOWING 1-10 OF 52 REFERENCES
PANDAS: current status and directions for research
TLDR
The recognition of the five criteria for PANDAS by Swedo et al established a homogenous subgroup of children with childhood onset obsessive–compulsive disorder (OCD) and/or tic disorders that is theorized to occur as a result of post-streptococcal autoimmunity in a manner similar to that of Sydenham's chorea. Expand
Infection-triggered anorexia nervosa in children: clinical description of four cases.
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TLDR
There may be a link between infectious disease and some cases of Anorexia nervosa, which raises the possibility of new treatment. Expand
The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup: separating fact from fiction.
TLDR
Questions about the veracity of data presented in this issue of Pediatrics are raised and a brief literature review and clarification of the guidelines for management of a patient in the PANDAS subgroup are provided. Expand
The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) etiology for tics and obsessive-compulsive symptoms: hypothesis or entity? Practical considerations for the clinician.
TLDR
Until more definitive scientific proof is forthcoming, there seems to be insufficient evidence to support routine microbiologic or serologic testing for group A streptococcus in children who present with neuropsychiatric symptoms or the clinical use of antibiotic or immune-modifying therapies in such patients. Expand
Is Tourette's syndrome an autoimmune disease?
We provide a review of recent research findings which support the involvement of autoimmunity in childhood-onset tic disorders, in particular the presence of antineuronal autoantibodies, D8/17 BExpand
Anti-brain antibodies in PANDAS versus uncomplicated streptococcal infection.
TLDR
The results suggest that antibrain antibodies are present in children with PANDAS that cannot be explained merely by a history of GABHS infection. Expand
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases.
TLDR
The working diagnostic criteria appear to accurately characterize a homogeneous patient group in which symptom exacerbations are triggered by GABHS infections. Expand
PANDAS: a commentary.
TLDR
It is concluded that PANDAS is an intriguing hypothesis that requires further confirmation, and antibodies produced against GABHS cross-react with neuronal cells, in a process involving molecular mimicry. Expand
Case study: a new infection-triggered, autoimmune subtype of pediatric OCD and Tourette's syndrome.
TLDR
The hypothesis is that infections with group A beta-hemolytic streptococci, among others, may trigger autoimmune responses that cause or exacerbate some cases of childhood-onset obsessive-compulsive disorder (OCD) or tic disorders (including Tourette's syndrome). Expand
Sydenham's chorea--clinical and evolutive characteristics.
TLDR
Despite the regular use of secondary benzathine penicillin prophylaxis, children with rheumatic fever have a high risk of Sydenham's chorea recurrence. Expand
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