REVIEW: Spermatozoa, DNA binding and transgenic animals

@article{Gandolfi1998REVIEWSD,
  title={REVIEW: Spermatozoa, DNA binding and transgenic animals},
  author={F Gandolfi},
  journal={Transgenic Research},
  year={1998},
  volume={7},
  pages={147-155}
}
The idea that sperm cells could be used as an effective tool for introducing exogenous DNA into an oocyte at fertilization is generally regarded with scepticism. However, in recent years, several investigators have been working on different aspects of this intriguing research topic. In the present review, their results are summarised and discussed. Sections have been dedicated to the way DNA molecules bind to spermatozoa of different species, to the events regulating such binding, to the fate… CONTINUE READING

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