REVIEW: Small Bowel Review: Normal Physiology, Part 2

  title={REVIEW: Small Bowel Review: Normal Physiology, Part 2},
  author={Alan B. R. Thomson and Laurie A. Drozdowski and Claudiu Iordache and Ben K.A. Thomson and S{\'e}verine Vermeire and Michael Tom Clandinin and Gary Wild},
  journal={Digestive Diseases and Sciences},
3 Citations

Ultrasound imaging for assessing functions of the GI tract

The main findings show the use of ultrasound to study esophageal motility, measure volume and contractility of the stomach, assess Motility, wall thickness, and perfusion of the small bowel, and evaluate wall vascularization and diameters of the large bowel.

Motility Disorders of the Stomach and Small Intestine

  • J. BarrR. White
  • Medicine
    Shackelford's Surgery of the Alimentary Tract, 2 Volume Set
  • 2019

Implication of gliadin toxicity on actin integrity and subsequent protein trafficking in vitro

The present study aimed to elucidate the gliadin-induced rearrangements of the actin cytoskeleton on the molecular level and to investigate this effect on subsequent protein trafficking.



IV. GABAB receptors in the brain-gastroesophageal axis

In the brain-gastroesophageal axis, a role has recently been demonstrated for GABAB receptors on extrinsic afferent endings within the stomach and esophagus, where they reduce mechanosensitivity.

Site-specific changes in transforming growth factor-α and -β1 expression in colonic mucosa of adolescents with inflammatory bowel disease

Adolescent IBD is characterized by a normal expression of TGF-alpha and -beta1 peptide and mRNA in the colonic epithelium but by an increased density of T GF-beta1-positive immune cells in the lamina propria during disease activity, suggesting a role in inflammatory modulation in IBD.

Blockade of GRP receptors inhibits gastric emptying and gallbladder contraction but accelerates small intestinal transit

Data show that BIM26226 is a potent antagonist of exogenous and endogenous GRP and suggest that GRP is a major physiologic regulator of gastric emptying, small bowel transit, and gallbladder contraction.

Intestinal development of early-weaned piglets receiving diets supplemented with selected amino acids or polyamines

Arginine and glutamate supplementation prevented weaning-induced wean-induced intestinal development and enhanced both total and mucosal growth in several sections of the small intestine, whereas polyamines were detrimental to intestinal growth.

Early acquisition of bowel segment-specific Bcl-2 homolog expression profiles during development of the human ileum and colon.

The expression of Bcl-2 homologs is modulated differentially during human gut development in order to establish, by mid-gestation, distinct expression profiles for the small and large intestines, suggests that gut segment-specific control mechanisms of human intestinal apoptosis are acquired early during fetal life.

Pseudo-obstruction: current approaches.

Effect of the Central Nervous System on Mucosal Growth and Apoptosis in the Small Intestine

The preliminary data showed that intestinal mucosal apoptosis decreased in the ventromedial-hypothalamus-lesioned rat, indicating that the central nervous system, in addition to local factors, is related to regulation of mucosal homeostasis in the intestinal mucosa.

Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells

Investigation of the effects of two isomers of CLA on Caco-2 cell transepithelial resistance (TER) development, paracellular epithelial permeability, and occludin and ZO-1 expression found that the trans-10 CLA isomer delayed the acquisition of transe Pithelial resistance and altered the cellular distribution of occlUDin, which have important implications in relation to epithelium permeability.