REVIEW: Antibacterial Therapy for Crohn's Disease: A Review Emphasizing Therapy Directed Against Mycobacteria

@article{Hultn2000REVIEWAT,
  title={REVIEW: Antibacterial Therapy for Crohn's Disease: A Review Emphasizing Therapy Directed Against Mycobacteria},
  author={Kristina G. Hult{\'e}n and Ashraf Almashhrawi and Fouad A. K. El-Zaatari and David Y Graham},
  journal={Digestive Diseases and Sciences},
  year={2000},
  volume={45},
  pages={445-456}
}
The most commonly used antibiotics in Crohn's disease are nitroimidazoles and macrolides often combined with corticosteroids or sulfasalazine. There has been interest in a mycobacterial involvement in Crohn's disease since its earliest description. It is not recognized that Mycobacterium avium subspecies paratuberculosis, a proven but uncommon cause of human disease, is widespread in the human food chain especially in dairy products and beef. M. paratuberculosis has been identified in tissues… CONTINUE READING