REVERSIBILITY IN EVOLUTION CONSIDERED FROM THE STANDPOINT OF GENETICS 1

@article{Muller1939REVERSIBILITYIE,
  title={REVERSIBILITY IN EVOLUTION CONSIDERED FROM THE STANDPOINT OF GENETICS 1},
  author={H. Muller},
  journal={Biological Reviews},
  year={1939},
  volume={14}
}
  • H. Muller
  • Published 1939
  • Biology
  • Biological Reviews
1. In Drosophila the great majority of mutations are reversible in direction, and very commonly the “reverse mutation” appears to reconstitute precisely the original gene. The mutation from the normal to the abnormal type has been found usually to be a change from a more active to a less active condition of the gene, and is hence to be regarded as constituting, itself, a reversal of the original direction of evolution. The so‐called reverse mutation, in such a case, is really a mutation in the… Expand
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RATE-GENES AND SELECTION THE results of selection at one period of the life-cycle may have repercussions on other periods and affect the species as a whole in unexpected ways. Perhaps the bestExpand
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WHEN it was discovered that chromosome breakage and reattachment usually entail effects resembling those of gene mutations located at or very near the point of breakage, it was suggested, as oneExpand
On the Meaning and Limits of Irreversibility of Evolution
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CONTRIBUTIONS OF CHEMICAL PHYSIOLOGY TO THE PROBLEM OF REVERSIBILITY IN EVOLUTION
1. It has been the object of this article to draw attention to biochemical and physiological evidence which supports the generalization known as Dollo's Law, side by side with palaeontological andExpand
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Page 108, last line of text, for "P/P″" read "P′/P″." Page 120, last line, for "δ v " read "δ y ." Page 123, line 10, for "4Nn" read "4Nu." Page 125, line 1, for "q" read "q." Page 126, line 12,Expand
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