RETRACTED ARTICLE: Pttg1 inhibits TGFβ signaling in breast cancer cells to promote their growth

@article{Zhang2014RETRACTEDAP,
  title={RETRACTED ARTICLE: Pttg1 inhibits TGFβ signaling in breast cancer cells to promote their growth},
  author={Guofeng Zhang and Qicheng Zhao and Songlin Yu and Rui Lin and Xianghua Yi},
  journal={Tumor Biology},
  year={2014},
  volume={36},
  pages={199-203}
}
Increased expression of Pituitary Tumor Transforming Gene 1 (Pttg1) has been shown in various tumor cells, including breast cancer (BC). However, the precise role of Pttg1 in the tumorigenesis is not clarified yet. Here, we examined BC from the patients and detected significant increases and correlation in Pttg1 and phosphorylated SMAD3 (pSMAD3), a key effector of activated transforming growth factor β (TGFβ) receptor signaling pathway. Pttg1 levels were then modulated by transgene or small… CONTINUE READING
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and breast cancer metastasis

  • Y Drabsch, P tenDijke
  • 2012

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