RET/PTC activation in hyalinizing trabecular tumors of the thyroid.

  title={RET/PTC activation in hyalinizing trabecular tumors of the thyroid.},
  author={Mauro Papotti and Marco Volante and Ada Giuliano and Ambrogio Fassina and Alfredo Fusco and Gianni Bussolati and Massimo Santoro and Gennaro Chiappetta},
  journal={The American journal of surgical pathology},
  volume={24 12},
Hyalinizing trabecular tumor (HTT) of the thyroid is a neoplasm of follicular derivation with a histogenesis that is still the subject of debate. Morphologic affinities between HTT and papillary carcinoma, including nuclear pseudoinclusions and grooves, suggest that these tumors may be of similar origin. The authors investigated the relationship between these two types of tumors by assessing HTT for the presence of rearrangements of the proto-oncogene rearranged during transfection (RET) that… CONTINUE READING


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