RER(+) phenotype in prostate intra-epithelial neoplasia associated with human prostate-carcinoma development.

@article{Miet1999RERPI,
  title={RER(+) phenotype in prostate intra-epithelial neoplasia associated with human prostate-carcinoma development.},
  author={S M Miet and Marc Neyra and Richard Jaques and Pierre Dubernard and Andr{\'e} Revol and Christophe Marçais},
  journal={International journal of cancer},
  year={1999},
  volume={82 5},
  pages={635-9}
}
The mutator (RER(+)) phenotype has been shown to be a mutational mechanism for tumour-suppressor-gene inactivation in colorectal cancer. A group of 60 prostate-carcinoma patients was studied to determine the frequency, intratumour distribution and timing of mutator phenotype in this cancer. Ten microsatellite loci were analyzed in 172 carcinoma foci (CF… CONTINUE READING