REM sleep enhancement by bupropion in depressed men.

  title={REM sleep enhancement by bupropion in depressed men.},
  author={Eric A. Nofzinger and Charles F. Reynolds and Michael E. Thase and Ellen Frank and J. Richard Jennings and Amy L Fasiczka and Lisa Sullivan and David Jerome Kupfer},
  journal={The American journal of psychiatry},
  volume={152 2},
OBJECTIVE The authors compared the effects of bupropion, fluoxetine, and cognitive behavior therapy on EEG sleep in depressed subjects. METHOD All-night sleep EEG studies were performed before treatment and after partial or full remission on 18 men with depression diagnosed according to Research Diagnostic Criteria and randomly assigned to treatment with either bupropion (N = 7) or fluoxetine (N = 11). Response to these drugs was measured by changes in Hamilton Depression Rating Scale scores… CONTINUE READING