REM sleep diversity following the pedunculopontine tegmental nucleus lesion in rat.

@article{Petrovi2014REMSD,
  title={REM sleep diversity following the pedunculopontine tegmental nucleus lesion in rat.},
  author={Jelena Petrovi{\'c} and Katarina Lazic and A. Kalauzi and Jasna Saponjic},
  journal={Behavioural brain research},
  year={2014},
  volume={271},
  pages={258-68}
}
The aim of this study was to demonstrate that two REM clusters, which emerge following bilateral pedunculopontine tegmental nucleus (PPT) lesions in rats, are two functionally distinct REM states. We performed the experiments in Wistar rats, chronically instrumented for sleep recording. Bilateral PPT lesions were produced by the microinfusion of 100 nl of 0.1M ibotenic acid (IBO). Following a recovery period of 2 weeks, we recorded their sleep for 6h. Bilateral PPT lesions were identified by… CONTINUE READING
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