REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA

@article{Gilman2003REMSB,
  title={REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA},
  author={Sid Gilman and Robert A. Koeppe and Ronald D. Chervin and Flavia B. Consens and Roderick J. A. Little and Hyonggin An and Larry Junck and Mary Heumann},
  journal={Neurology},
  year={2003},
  volume={61},
  pages={29 - 34}
}
Objective: To explore the neurochemical basis of REM sleep behavior disorder (RBD) in multiple-system atrophy (MSA). Methods: In 13 patients with probable MSA, nocturnal, laboratory-based polysomnography was used to rate the severity of REM atonia loss by the percentage of REM sleep with tonically increased electromyographic (EMG) activity and the percentage of REM sleep with phasic EMG bursts. PET with (+)-[11C]dihydrotetrabenazine ([11C]DTBZ) was employed to measure the density of striatal… 
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