REM sleep behavior disorder

@article{FeriniStrambi2000REMSB,
  title={REM sleep behavior disorder},
  author={Luigi Ferini-Strambi and Marco Zucconi},
  journal={Clinical Neurophysiology},
  year={2000},
  volume={111},
  pages={S136-S140}
}

REM behavior disorder in children

TLDR
Rapid eye movement sleep behavior disorder, also called REM behavior disorder (RBD), is a condition characterized by loss of REM atonia, vivid dreaming, and dream-enacting motor activity or vocalizations that can at times lead to injury to self or others.

Sleep Dysfunction in Multiple System Atrophy

TLDR
CPAP is an effective treatment for eliminating obstructive sleep apnea in MSA patients, even if the adaptation to the device may be difficult in advanced cases.

Review of rapid eye movement behavior sleep disorders

TLDR
The spectrum of rapid eye movement behavior disorders (RBD) spans various age groups, with the greatest prevalence in elderly men, and is hypothesized to be caused by primary dysfunction of the pedunculo-pontine nucleus or other key brainstem structures associated with basal ganglia pathology.

Idiopathic Rapid Eye Movement Sleep Behavior Disorder Is a Harbinger of Dementia with Lewy Bodies

TLDR
Inclusion of historical or concurrent idiopathic RBD in the diagnostic criteria for DLB may improve their sensitivity, specificity, and clinical utility.

REM sleep behavior disorder in the marmoset MPTP model of early Parkinson disease.

TLDR
Investigating sleep changes in marmoset monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP), the non-human primate model for idiopathic PD, suggests that the MPTP marmosets model of PD could be used for further studies into the mechanisms and treatment of RBD and other sleep disorders in premotor symptom PD.

Acute levodopa dosing around-the-clock ameliorates REM sleep without atonia in hemiparkinsonian rats

TLDR
The findings show that the phenomenological correlates of RSWA can be reliably characterized in the hemiparkinsonian rat model of PD and suggest that further study may allow for the application of a similar approach to treat RBD in PD patients.

REM SLEEP BEHAVIOR DISORDER IN THE MARMOSET MODEL OF PD

TLDR
Investigating sleep changes in marmoset monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP), the non-human primate model for idiopathic PD, suggests that the MPTP marmosets model of PD could be used for further studies into the mechanisms and treatment of RBD and other sleep disorders in premotor symptom PD.

Sleep disorders in Parkinson’s disease

  • C. Comella
  • Psychology, Medicine
    Current treatment options in neurology
  • 2008
TLDR
Excessive daytime sleepiness related to the use of direct dopaminergic agonists may improve with dosage reduction or discontinuation, and Stimulants such as modafinil may provide modest benefit.

Sleep-related epilepsy.

  • M. Zucconi
  • Psychology, Medicine
    Handbook of clinical neurology
  • 2011

References

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REM sleep behavior disorder and degenerative dementia

TLDR
A group of predominantly male patients with a characteristic association of RBD and degenerative dementia is reported, and it is hypothesized that the underlying pathology in these patients is DLB.

Chronic behavioral disorders of human REM sleep: a new category of parasomnia.

TLDR
These REM sleep neurobehavioral disorders constitute another category of parasomnia, replicate findings from 21 years ago in cats receiving pontine tegmental lesions, and offer additional perspectives on human behavior, neurophysiology, pharmacology, and dream phenomenology.

REM sleep behavior disorders in multiple system atrophy

TLDR
It is shown that RBD represents the most common clinical sleep manifestation and polysomnographic finding in patients with MSA and can frequently herald the appearance of other MSA symptoms by years.

Nocturnal frontal lobe epilepsy: Sporadic versus familial cases

TLDR
The aims of the present study were to identify, on the basis of a full-night video-polysomnography, the differential features, if any, between parasomnia and NFLE and between familial and sporadic form of NFLE.

Incidental Lewy body disease in a patient with REM sleep behavior disorder

Article abstract-We studied an 84-year-old man with a 20-year history of nocturnal violent behavior during sleep, but no other clinically evident neuropsychiatric disorders. Polysomnographic

A controlled study of serum anti-locus ceruleus antibodies in REM sleep behavior disorder.

TLDR
It is unlikely that human RBD is associated with anti-LC antibodies, however, an autoimmune process in RBD has not been excluded by this study.

Different behaviors during paradoxical sleep without atonia depend on pontine lesion site

Diagnosis and treatment of sleep disorders caused by co-morbid disease.

TLDR
The diagnosis of the co-morbidity is the first step in treatment, followed by an assessment of the sleep disturbance, which begins with a complete history and physical examination and laboratory testing such as polysomnography, multiple sleep latency testing, and actigraphy.

Cardiac autonomic activity during wakefulness and sleep in REM sleep behavior disorder.

TLDR
This study shows that only 36% of patients had normal results in all traditional autonomic tests during wakefulness, and RBD patients had a reduced tonic and phasic heart rate variability during sleep.