REM Sleep at its Core – Circuits, Neurotransmitters, and Pathophysiology


Rapid eye movement (REM) sleep is generated and maintained by the interaction of a variety of neurotransmitter systems in the brainstem, forebrain, and hypothalamus. Within these circuits lies a core region that is active during REM sleep, known as the subcoeruleus nucleus (SubC) or sublaterodorsal nucleus. It is hypothesized that glutamatergic SubC neurons… (More)
DOI: 10.3389/fneur.2015.00123


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