REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP.

  title={REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP.},
  author={Pascal M Ravassard and Al Mahdy Hamieh and Micka{\"e}l Antoine Joseph and Nicolas P Fraize and Paul-Antoine Libourel and L{\'e}a Lebarillier and S{\'e}bastien Arthaud and Claire Meissirel and Monique Touret and Ga{\"e}l Malleret and Paul-Antoine Salin},
  journal={Cerebral cortex},
  volume={26 4},
Prolonged rapid-eye-movement (REM) sleep deprivation has long been used to study the role of REM sleep in learning and memory processes. However, this method potentially induces stress and fatigue that may directly affect cognitive functions. Here, by using a short-term and nonstressful REM sleep deprivation (RSD) method we assessed in rats the bidirectional influence of reduced and increased REM sleep amount on hippocampal-dependent emotional memory and plasticity. Our results indicate that 4… CONTINUE READING
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