REM Sleep Behavior Disorder and other sleep abnormalities in p. A53T SNCA mutation carriers.

  title={REM Sleep Behavior Disorder and other sleep abnormalities in p. A53T SNCA mutation carriers.},
  author={A. Simitsi and C. Koros and M. Stamelou and D. Papadimitriou and Athanasios Leonardos and A. Bougea and N. Papagiannakis and I. Pachi and Efthalia Angelopoulou and Konstantinos Lourentzos and A. Bonakis and L. Stefanis},
STUDY OBJECTIVES Τo assess whether REM Sleep Behavior Disorder (RBD) and other sleep abnormalities occur in carriers of the p.A53T alpha-synuclein gene (SNCA) mutation, using both subjective and objective measures. METHODS We have assessed 15 p.A53T carriers [10 manifesting Parkinson's Disease (PD-A53T) and 5 asymptomatic carriers] with simultaneous Video-PSG (polysomnography) recording, the Epworth Sleepiness Scale (ESS) for daytime sleepiness, the Athens Insomnia Scale (AIS), the RBD… Expand


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