REG3β Plays a Key Role in IL17RA Protumoral Effect-Letter.

@article{Li2016REG3PA,
  title={REG3β Plays a Key Role in IL17RA Protumoral Effect-Letter.},
  author={Qicai Li and Junli Liu and Zu-Hua Gao},
  journal={Cancer research},
  year={2016},
  volume={76 7},
  pages={
          2050
        }
}
We have read with great interest the recent report by Loncle and colleagues ([1][1]) investigating the role of REG3β in mediating protumoral effects of IL17. We agree in principal with their conclusion that Reg3β is involved in the initiation of pancreatic ductal adenocarcinoma (PDAC) and its 
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IL-17 functions through the novel REG3b-JAK2-STAT3 inflammatory pathway to promote the transition fromchronic pancreatitis to pancreatic cancer

C Loncle, L Bonjoch, +3 authors MolejonMI
  • Cancer Res
  • 2015
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