RED CELLS Identification of the Poly ( C ) Binding Protein in the Complex Associated With the 3 8 Untranslated Region of Erythropoietin Messenger RNA

@inproceedings{CzyzykKrzeska1999REDCI,
  title={RED CELLS Identification of the Poly ( C ) Binding Protein in the Complex Associated With the 3 8 Untranslated Region of Erythropoietin Messenger RNA},
  author={Maria F. Czyzyk-Krzeska and Amy C. Bendixen},
  year={1999}
}
Hypoxia regulates expression of erythropoietin (EPO), a glycoprotein that stimulates erythrocytosis, at the level of transcription and also possibly at the level of messenger RNA (mRNA) stability. A pyrimidine-rich region within the EPO mRNA 38 untranslated region was implicated in regulation of EPO mRNA stability element and shown to bind protein factors. In the present study we wished to identify the protein factor binding to the pyrimidine-rich sequence in the EPO mRNA stability element… CONTINUE READING
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