• Corpus ID: 36315887

RED CELLS , IRON , AND ERYTHROPOIESIS Erythroferrone contributes to recovery from anemia of in fl ammation

  title={RED CELLS , IRON , AND ERYTHROPOIESIS Erythroferrone contributes to recovery from anemia of in fl ammation},
  author={L{\'e}on Kautz and Grace Jung and Elizabeta Nemeth and Tomas Ganz},
Anemia of inflammation (AI) is a common feature of inflammatory disorders, including connective tissue diseases, infections, certain cancers, and chronic kidney disease. AI is characterized by a normocytic normochromic anemia with a shortened erythrocyte lifespan and impaired erythropoiesis, despite adequate levels of circulating erythropoietin (EPO). Disordered iron homeostasis is consistently observed in AI and is manifested by hypoferremia with intact iron stores but decreased iron… 

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