RECORD: a novel method for ordering loci on a genetic linkage map

@article{Os2005RECORDAN,
  title={RECORD: a novel method for ordering loci on a genetic linkage map},
  author={Hans van Os and Piet Stam and Richard G. F. Visser and Herman van Eck},
  journal={Theoretical and Applied Genetics},
  year={2005},
  volume={112},
  pages={30-40}
}
A new method, REcombination Counting and ORDering (RECORD) is presented for the ordering of loci on genetic linkage maps. The method minimizes the total number of recombination events. The search algorithm is a heuristic procedure, combining elements of branch-and-bound with local reshuffling. Since the criterion we propose does not require intensive calculations, the algorithm rapidly produces an optimal ordering as well as a series of near-optimal ones. The latter provides insight into the… CONTINUE READING
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