REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics

@article{CarhartHarris2019REBUSAT,
  title={REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics},
  author={R. Carhart-Harris and Karl J. Friston},
  journal={Pharmacological Reviews},
  year={2019},
  volume={71},
  pages={316 - 344}
}
  • R. Carhart-Harris, Karl J. Friston
  • Published 2019
  • Medicine, Psychology
  • Pharmacological Reviews
  • This paper formulates the action of psychedelics by integrating the free-energy principle and entropic brain hypothesis. [...] Key Result With regard to their potential therapeutic use, we propose that psychedelics work to relax the precision weighting of pathologically overweighted priors underpinning various expressions of mental illness.Expand Abstract
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