• Corpus ID: 99714348

REACTION OF ARYL- AND HETEROARYL BENZOYL- AND ACETYLHYDRAZONES WITH PHENYLISOCYANATE SYNTHESIS OF SUBSTITUTED-2,3-DIHYDRO-1,3,4- OXADIAZOLES

@article{Awadallah2016REACTIONOA,
  title={REACTION OF ARYL- AND HETEROARYL BENZOYL- AND ACETYLHYDRAZONES WITH PHENYLISOCYANATE SYNTHESIS OF SUBSTITUTED-2,3-DIHYDRO-1,3,4- OXADIAZOLES},
  author={Adel M. Awadallah},
  journal={IUG Journal of Natural Studies},
  year={2016},
  volume={14}
}
  • A. Awadallah
  • Published 13 February 2016
  • Chemistry
  • IUG Journal of Natural Studies
Aryl benzoylhydrazones (1a-c) react readily with phenylisocyanate (2) at room temperature to give the corresponding substituted 2,3-dihydro-1,3,4-oxadiazoles (3a-c). On the other hand, the reaction of benzoylhydrazones of furan, thiophene and pyridine carbaldehydes gave 2,5-dioxo-1,5-diphenyl-1,3,4-triazapentane (4), and that of theiophene acetylhydrazone gave 2,5-dioxo-1-phenyl-1,3,4- triazahexane (5). Structure elucidation of these compounds was based on spectral data including IR, Ms and NMR…