RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.

@article{Lotz2004RBR1AN,
  title={RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.},
  author={Henrike Lotz and Kai Sohn and Herwig Brunner and Fritz A Muhlschlegel and Steffen Rupp},
  journal={Eukaryotic cell},
  year={2004},
  volume={3 3},
  pages={
          776-84
        }
}
The transcription factor Rim101p of Candida albicans has been shown to play a major role in pH-dependent gene regulation. Rim101p is involved in cell wall biosynthesis, since it regulates PHR1 and PHR2, two almost functionally redundant cell wall glycosidases important for adaptation to either neutral or acidic habitats within the human host. To identify additional cell wall components regulated by Rim101p, we performed transcriptional profiling with a cell wall-specific DNA microarray. We… CONTINUE READING
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