RBE measurements in the epithelial megacolony , a simplified in vitro tumour model

Megacolonies generated from squamous carcinoma cells are tightly packed quasi-epithelial aggregates, organized into a highly proliferative marginal rim and a multilayered contactinhibited core region [1]. Using a murine cell line (AT478) this model has been employed to quantify RBE values of the accelerated carbon ion beam versus a Cs-137 reference source… CONTINUE READING